Artificial Intelligence
The proposal would redevelop part of the former Portsmouth uranium-enrichment complex, pairing a major local grant fund with statewide AI-tool credits for Ohio college students while committing to fund its own grid and water infrastructure.
Capital + Deals
The proposed transaction would place Joby’s defense aircraft and autonomy programs within Resonant’s Dayton operation, combining its electric propulsion technology with RF sensing, mission systems and low-observability expertise.
Healthcare
Backed by Ohio State’s medical, cancer and pharmacy assets, the new effort will pair AI with clinical and genomic data to speed the path from research to patents, startup formation and clinical trials—an added push for Central Ohio’s life-sciences sector.
Fueled by logistics dominance and aggressive site development, the state’s rise reflects years of coordinated economic strategy. Major investments in semiconductors, energy, and AI infrastructure are accelerating its position as a national hub for industrial-scale innovation.
AI25, presented by Ohio Tech News and OhioX, recognizes leaders turning artificial intelligence into real-world impact across Ohio — from startups and classrooms to hospitals, public agencies, manufacturing floors, and the capital backing what comes next.
Resilience’s move from San Diego to Blue Ash cements Southwest Ohio as a million‑square‑foot hub for sterile injectables and advanced packaging, tying corporate leadership directly to its expanding West Chester manufacturing network and new high‑skill jobs in the region.
Facing a projected shortage of more than 540,000 skilled workers over the next decade, Ohio is launching a $300 million workforce initiative. The program aims to reach roughly 25,000 Ohioans by providing financial incentives for hybrid work-and-education models in critical industries.
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Combining an AI-native security platform with human expertise, the Cleveland firm helps underserved mid-market companies prioritize critical threats. By mapping operational risks and running tabletop exercises, the team guides clients past tool clutter to protect vital systems.
Powered by AI claims processing and an in-person Central Ohio workforce, Priyang Shah's health startup helps employers cover out-of-pocket costs for dual-income families. Backers include Y Combinator and First Round Capital, alongside local investor North Coast Ventures.
The Cleveland-based nonprofit venture development organization, has added two executives to its leadership team, naming Terri Bradford Eason as its first chief revenue officer and Daniel Brown as chief services officer.
Columbus-built “physical AI” is moving from pilot to production in U.S. Navy shipyards, as HII signs a multi-year, performance-based automation deal worth up to $900 million — including a long-term, $600 million allocation that will be engineered out of Central Ohio.
Generative AI solved the code-creation problem, but legacy CI/CD systems are choking on the output. As autonomous agents take over the developer stack, serial founders Dan Manges and Tommy Graves are scaling the infrastructure needed to validate AI-generated code at machine speed.
Ohio’s healthcare innovators are confronting a persistent reality: promising technology only creates value when it works for clinicians and patients. That means designing around real workflows, adoption barriers and the people at the center of care.
Spearheaded by the ESP network and targeted scaling programs like CapitalReady, the nonprofit's support fueled a 60% surge in small business output. By connecting founders to vetted partners, the strategy prepares Ohio tech startups to lead in AI and health.
AI25, presented by Ohio Tech News and OhioX, recognizes leaders turning artificial intelligence into real-world impact across Ohio, from startups and classrooms to hospitals, public agencies, manufacturing floors, and the capital backing what comes next.
Defense Innovation OnRamp Hub: Ohio is accepting applications for a new dual-use technology accelerator focused on edge AI, autonomy, advanced sensors, resilient communications and other tools built for contested environments. Applications close July 31.
Billions are landing in advanced manufacturing, life sciences, aerospace and AI infrastructure. Companies are moving headquarters here, founders are raising big rounds here, and a state now ranked No. 1 for business is building the workforce to match. Capital, deals and jobs from recent weeks.
The Third Coast Foundry creates a Silicon Valley foothold for university-backed startups, offering direct access to investors, programming and partnerships while aiming to keep company growth, talent and operations anchored in the region.
The semi-autonomous fighter, built for the Air Force's Collaborative Combat Aircraft program, took 126 days to assemble on a line that started three months ahead of schedule and can produce up to 150 aircraft a year — 143 workers hired in under 12 months are first of future 4,000 people on site.
